I-17α-Hydroxyprogesterone CAS 68-96-2

Intshayelelo 17 α- I-Hydroxyprogesterone, ngamanye amaxesha ebizwa ngokuba yi-Hydroxyprogesterone (ngesiNgesi: i-hydroxyprogesterone, i-OHP), yi-progesterone steroid ephuma emzimbeni efana ne-progesterone, kwaye ikwangunobangela we-biosynthesis yee-hormone ezininzi ze-steroid ephuma emzimbeni, kubandakanya i-androgen, i-estrogen, i-glucocorticoid, i-mineralocorticoid kunye nezinye ii-neurosteroids. I-Bioactive 17-Hydroxyprogesterone (17-OHP) yi-progesterone ephuma emzimbeni kunye ne-chemical intermediate kwi-biosynthesis yezinye ii-hormone ze-steroid. Izifundo ze-in vitro 17 α- OHP yi-progesterone efana ne-chemobookin receptor agonist, nangona isiphumo sayo sibuthathaka. Ikwayi-chemical intermediate kwi-biosynthesis yee-hormone ze-steroid ezifana ne-androgens, i-estrogen, ii-hormone zesini, ii-glucocorticoids, kunye ne-mineralocorticoids. Isifundo se-in vivo 17 I-Hydroxyprogesterone yi-steroid inducer esebenzayo ye-GVBD (ukuqhekeka kwe-vesicle yokuzala). Iimpawu zeekhemikhali ze-crystallization (i-acetone/hexane). Iqondo lokunyibilika 221 ℃ (219-220 ℃). [α] 20/D+97 ° (chlorofor