I-Praziquantel: i-agent enamandla ye-antiparasite yonyango oludibeneyo kunye nokuthintela

PraziquantelYi-arhente egqwesileyo eyaziwayo ngokusebenza kwayo okubanzi ngokuchasene nosulelo lwezifunxi-gazi.I-Praziquantel inerekhodi eqinisekisiweyo yonyango kunye nothintelo lwe-schistosomiasis, i-cysticercosis, i-paragonimiasis, i-echinococcosis, i-zingiberiasis kunye nosulelo lwe-helminth kwaye ngaloo ndlela idlala indima ebalulekileyo ekulweni nezi zifo eziphazamisayo.

I-Schistosomiasis, eyaziwa njenge-snail fever, sisifo esingahoywayo esibangelwa sisifunxi-gazi.Ichaphazela izigidi zabantu ehlabathini lonke, ingakumbi kwimimandla ehlwempuzekileyo enenkqubo yogutyulo engekho mgangathweni nokufikelela okulinganiselweyo kumanzi acocekileyo.PraziquantelIfunyaniswe isebenza kakhulu ekupheliseni i-schistosome parasite ebangela esi sifo.Ngokujolisa kwiinkqubo zemithambo-luvo yeentshulube,ipraziquantelbababulale ngempumelelo, nto leyo evumela izigulana ukuba zichache kwesi sifo sibeka ubomi esichengeni.

I-Cysticercosis ebangelwa yimibungu ye-solium sesinye isifo esiyingozi esinokunyangwa ngokufanelekileyo kwaye sithintelwe nge-praziquantel.Ngokuhlasela nokutshabalalisa imibungu efakwe kwizihlunu ezahlukeneyo, i-praziquantel iyayeka ukukhula kwe-cysticercosis kwaye ithintele iingxaki ezingakumbi ezifana nokuxhuzula kunye nomonakalo womthambo.Ukukwazi kwechiza ukujolisa ezi zimfimfithi ngelixa kuncitshiswa iziphumo ebezingalindelekanga kuyenza ibe sisixhobo esixabisekileyo kumlo ochasene nesi sifo singumngeni.

I-Paragonimiasis, ebonakaliswa lusulelo lwe-lung fluke, ixhaphakile kwiindawo apho iicrustaceans ezikrwada okanye ezingaphekwanga ngokwaneleyo zamanzi acocekileyo zityiwa.Iimpawu ziqala ukukhohlela okungapheliyo kunye neentlungu zesifuba ukuya kwisikhohlela esinegazi kunye noxinzelelo lokuphefumla.I-Praziquantel isetyenziswa ngokubanzi ukulawula i-paragonimiasis ngenxa yeziphumo zayo ezimangalisayo zokutshabalalisa izinambuzane kunye neziphumo zokuphelisa iimpawu.Ngonyango olululo lwepraziquantel, izigulana zinokuchacha kwaye zithintele ukubuya kwesi sifo sibi.

Isifo se-Hydatid, isifo sejinja, kunye nosulelo lwe-parasitic worm zezinye iimeko apho i-praziquantel iboniswe ukuba isebenza kakhulu.Njenge-antiparasitic ebanzi, i-praziquantel ijolise kwaye itshabalalisa iintsholongwane ezibangela ezi zifo, inika izigulane ithuba lokuchacha kunye nokuphucula umgangatho wobomi.

Ukuqukumbela, ipraziquantel sisixhobo esixabiseke kakhulu ngokuchasene nosulelo lwezifunxi-gazi ezahlukeneyo.Ukusebenza kwayo, kudityaniswa neendleko zayo eziphantsi kunye neziphumo ebezingalindelekanga ezincinci, kuyenza isetyenziswe zizigidi zabantu emhlabeni jikelele.Nokuba iyanyanga kwaye iyasikhusela i-schistosomiasis, i-cysticercosis, i-paragonimiasis, i-echinococcosis, i-zingiberiasis okanye usulelo lwe-parasitic, i-praziquantel iyaqhubeka nokuba nefuthe elihle kubomi babo bachaphazeleka kwezi zifo zifunxileyo.Masingakujongeli phantsi ukubaluleka kweliyeza elingaqhelekanga kwaye siqhubeke nokuxhasa uphando kunye namanyathelo awenza ukuba afumaneke kubo bonke abawudingayo.