Isifo Synthesis Synthesis yinkalo ebalulekileyo yophando lwale mihla kunye nemveliso yemveliso. Kubandakanya ukuveliswa kweendlela ezintsha zokuphendula ngemichiza, kunye ne-regent enye ephambili edlala indima ebalulekileyo kule nkqubo yi-sodium cyanoborohydride.
I-sodium cyanoborohydridedride, kunye nefomula yekhemicamicali Nabh3cn, yi-arhente yokuphucula i-arhente eqinileyo esetyenziswa rhoqo kwi-chemistry ye-organic. Ixabiso ngokukhethekileyo kukukwazi kwayo ngokukhethekileyo ukunciphisa i-AldeHYEYSE kunye neeKetos kwiziselo ezibandakanyekayo, ezenza isixhobo esibalulekileyo kwi-synthesicals, iikhemikhali ezihle, kunye nezinye izinto eziphilayo.
Esona sibonelelo siphambili sokusebenzisa isodium selanoborodyarohydride ukuba iarhente yokucutha ziimeko zawo ezilapho. Ngokungafaniyo nezinye iiarhente eziqhelekileyo ezisetyenziswayo ezifana ne-lithium alumnum hydride,I-sodium cyanoborohydridedrideImisebenzi phantsi kweemeko ezithobekileyo, iyenza ikhuseleke kwaye ilungele ukusetyenziswa kuseto lwelebhu. Obu buthathaka bavumela ukulawulwa okungcono kwendlela yokuphendula, ukunciphisa umngcipheko wokuphendula kwicala elingafunekiyo okanye ukunciphisa ukuncitshiswa kweethagethi.
Elinye iNyaniso enkulu yeI-sodium cyanoborohydridedridekukhetho lwayo oluphezulu. Xa isetyenziselwa ukunciphisa imigaqo ye-carbonyl, ngokubanzi ithintela ekungeneni kwamanye amaqela asebenza kwimolekyuli, okukhokelela ekucoceni nasekuphenduleni ngakumbi. Oku khetha ukukhetha kubalulekile kwi-synthesis yeemolekyuli ezihamba ezintsokothileyo, apho ukugcinwa kwamanye amaqela asebenza nzima kuhlala kubalulekile kwisakhiwo sekhemikhali esifunayo kunye neepropathi.
Ukongeza ekubeni yiarhente yokuphucula,I-sodium cyanoborohydridedrideinokusetyenziswa kwezinye iinguqu zemichiza. Ingasetyenziselwa ukuncitshiswa kwe-AldeHYEYDESS kunye neeKetones, kunye neSynthesis yeendlela ezahlukeneyo ze-heterocyclic. Ukusetyenziswa kwendlela yayo kunye nokuhambelana namaqela ohlukeneyo asebenza kwenza isixhobo esibalulekileyo semichiza ejongene nemiceli mngeni eyahlukeneyo.
Ukongeza,I-sodium cyanoborohydridedrideYaziwa ngokuqina kunye nokukhululeka kokuphatha. Ngokungafaniyo nezinye iirekhodi zokuphendula, zinokugcinwa kwaye zithuthwa ngaphandle kokuthatha amanyathelo aphezulu, zenza ukuba kube lula ngakumbi kwizicwangciso zemfundo kunye nezomzi-mveliso.
NangonaI-sodium cyanoborohydridedrideUnezibonelelo ezininzi, kubalulekile ukuba uqaphele ukuba, njengayo nayiphi na iarhente yekhemizi, kufuneka isuswe ngononophelo nasekulandeleni iinkqubo ezifanelekileyo zokhuseleko. Nangona kuthathwa njengento ekhuselekileyo kunenye yeearhente zokunciphisa, iseyimichiza enamandla kunye nezilumkiso ezifanelekileyo kufuneka ithathwe phantsi kwesikhokelo se-chemist.
Ukuququmbela,I-sodium cyanoborohydridedrideIdlala indima ebalulekileyo kwiSynthesis Synthesis, ngakumbi ekunciphisweni kweekhomputha zekhabhoni kunye nezinye iinguqu ezinxulumene noko. Iimeko zayo ezipholileyo, ukukhetha okuphezulu, izinto zokungaguquki, kunye nokuzinza kubenza i-asethi ebaluleke kakhulu kwibhokisi yezixhobo ze-chemist. Njengoko uphando kunye nophuhliso kwicandelo lemizi-chemisti ye-organic liyaqhubeka nokuqhubela phambili, ukubaluleka kweI-sodium cyanoborohydridedrideUkunika inguqu entsha yemichiza kunye ne-synthesis yeempawu ze-noovel ziya kuhlala zibalulekile.
IXESHA LOKUQALA: AUG-29-2024