I-Guanidine Thiocyanate isetyenziswa njenge-biomedicine, ii-reagents zamakhemikhali, njl. Ingasetyenziswa njenge-arhente ye-chaotropic kunye ne-denaturant kwi-denaturate kunye nokuqhawula iiseli, ukukhupha i-RNA kunye ne-DNA, kunye ne-adsorbent ye-DSSC ukuphucula izinga lokuguqulwa kwe-DSSC.