I-17α-Hydroxyprogesterone CAS 68-96-2

Intshayelelo 17 α- IHydroxyprogesterone, ngamanye amaxesha ibizwa ngokuba yiHydroxyprogesterone (isiNgesi: hydroxyprogesterone, OHP), yiprogesterone steroid engapheliyo efana neprogesterone, kwaye ikwayi-precursor ye-biosynthesis yeehomoni ezininzi ze-endogenous steroid, kubandakanya i-androgen, i-estrogen, iglucocorticoid, imineralocorticoid kunye ezinye neurosteroids.I-Bioactive 17-Hydroxyprogesterone (17-OHP) yiprogesterone engapheliyo kunye nekhemikhali ephakathi kwi-biosynthesis yezinye iihomoni ze-steroid.Izifundo ze-in vitro i-17 α- OHP yiprogesterone efana ne-chemobookin receptor agonist, nangona umphumo wayo ubuthathaka.Ikwayikhemikhali ephakathi kwi-biosynthesis yeehomoni ze-steroid ezifana ne-androgens, i-estrogen, iihomoni zesini, i-glucocorticoids, kunye ne-mineralocorticoids.Kwisifundo se-vivo i-17 i-Hydroxyprogesterone yi-inducer ye-steroid esebenzayo ye-GVBD (i-reproductive vesicle rupture).Iipropati zeMichiza i-crystallization (i-acetone / i-hexane).Indawo yokunyibilika 221 ℃ (219-220 ℃).[ α] 20/D+97 ° (chlorofor